Laboratory Test

Drugs as Per Drugs & Cosmetics Act

Test and Assay of Drugs Requiring Use of Animals

  • Pyrogen test
  • Abnormal or undue toxicity or safety test
  • Skin sensitivity/Eye irritancy test /Dermal toxicity
  • Heparin Identification

Microbiological Tests and Assays

  • Bioassay of Antibiotic
  • Microbiological assay of antibiotics, vitamins and amino acids
  • Phenol coefficient for black disinfectant fluids
  • Sterility test – Parenteral preparations, surgical dressings, syringes and needles, transfusion and infusion sets or assemblies, intra ocular lens, I.V. Canula
  • Bacterial Endotoxin
  • Microbial limit test

Identification Tests

  • Chemical
  • Microscopy
  • IR spectroscopy
  • UV spectroscopy

Chromatography

  • Thin layer chromatography
  • Gas chromatography
  • High performance liquid chromatography
  • High performance thin layer chromatography

Physical / Chemicals Tests and Determinations

  • Absorbency
  • Acid value
  • Adhesive strength
  • Alcohol content
  • Ash
  • Diagnostic –aids : Uri strip (Estimation of Glucose, Protein and pH)
  • Disintegration tests
  • Dissolution test
  • Extractable volume
  • Extractive value
  • Fluorescence
  • Foreign matter
  • Iodine value
  • Limit test for Arsenic
  • Limit test for Heavy metals
  • Limit test for impurities/ Controlled degradation
  • Loss on drying
  • Melting point
  • Needle attachment - Sutures
  • Net content
  • Optical rotation & Specific Optical rotation
  • Particle size and count
  • Particulate matter –Parenterals
  • Peroxide value
  • pH value
  • Physical requirement test of set, syringe, needles
  • Refractive index
  • Related substances
  • Saponification value
  • Solubility
  • Soluble extractives
  • Specific gravity
  • Sulphated ash
  • Tensile strength
  • Thread count
  • Total solids
  • Uniformity of content
  • Uniformity of dispersion
  • Uniformity of weight
  • Unsaponifiale matter
  • Viscosity
  • Volatile oil
  • Water (Karl Fisher)
  • Weight /unit area (surgical)
  • Weight per ml

Assays

  • General chemical methods
  • Non-aqueous/instrumental
  • Chromatography – HPLC, GC , HPTLC, AAS, Flame Photometry, IR

Sera and Vaccine

  • Sterility test
  • Testing of antisera for the specific titre

Rubber Condoms –(Schedule -R)

  • Dimensions
  • Water leakage test
  • Burst volume and burst pressure test

Food Products as Per Food Safety Standard Act

Microbiological Tests and Assays

  • Microbial limit test as per BIS

Identification Tests

  • Chemical
  • Microscopy

Chromatography

  • Paper chromatography
  • Thin layer chromatography
  • Column chromatography
  • Gas chromatography
  • High performance liquid chromatography
  • High performance thin layer chromatography

Physical / Chemical Tests and Determinations

  • Acid value
  • Ash
  • Cloud point
  • Extractive value
  • Flash point
  • Fluorescence
  • Foreign matter
  • Free fatty acid
  • Iodine value
  • Loss on drying
  • Melting point
  • Net content
  • Optical rotation
  • Peroxide value
  • pH value
  • Refractive index
  • Saponification value
  • Solubility
  • Specific gravity
  • Sulphated ash
  • Test for adulterant
  • Unsaponifiable matter
  • Viscosity
  • Weight per ml

Assays

  • General chemical methods
  • Non-aqueous/instrumental
  • Chromatography – HPLC, GC & HPTLC
  • U.V. / Visible Spectrophotometric tests
Go to Navigation